{
  "schemaVersion": 1,
  "source": {
    "title": "IMPRESIVE Sharing.pptx",
    "role": "Approved scientific source for public figures"
  },
  "databaseOrder": [
    "NHIRD",
    "CGRD",
    "NHIS",
    "HIRA",
    "DeSC",
    "CDARS"
  ],
  "databases": {
    "NHIRD": {
      "label": "NHIRD",
      "country": "Taiwan",
      "color": "#174a7e",
      "marker": "circle"
    },
    "CGRD": {
      "label": "CGRD",
      "country": "Taiwan",
      "color": "#2c7a4b",
      "marker": "square"
    },
    "NHIS": {
      "label": "NHIS",
      "country": "South Korea",
      "color": "#a55a00",
      "marker": "triangle"
    },
    "HIRA": {
      "label": "HIRA",
      "country": "South Korea",
      "color": "#6b4fa3",
      "marker": "diamond",
      "sourceMarker": "*"
    },
    "DeSC": {
      "label": "DeSC",
      "country": "Japan",
      "color": "#a33b6b",
      "marker": "cross"
    },
    "CDARS": {
      "label": "CDARS",
      "country": "Hong Kong",
      "color": "#007c91",
      "marker": "hexagon"
    }
  },
  "figures": {
    "ascvdRisk": {
      "title": "Recurrent ASCVD risk in very-high-risk versus high-risk groups",
      "sourceSlides": [
        38
      ],
      "guideline": "2018 AHA/ACC/Multi-society Guideline",
      "measure": "Hazard ratio",
      "reference": 1,
      "range": {
        "lower": 1.2,
        "upper": 1.6
      },
      "treatmentFinding": {
        "lowerPercent": 18,
        "upperPercent": 34,
        "statement": "Treatment intensity does not match risk: 18% to 34% were prescribed high-intensity statins during hospitalization."
      },
      "interpretation": [
        "Risk stratification was transferable across the represented East Asian settings.",
        "The very-high-risk group remained clinically distinct.",
        "Common-data-model results were broadly consistent overall.",
        "Terminology mapping was the main source of distortion."
      ],
      "notReportedOnSourceSlide": [
        "database-specific hazard ratios",
        "confidence intervals for the reported programme-level range",
        "analysis year",
        "denominator"
      ]
    },
    "adOutcomes": {
      "title": "Atopic-dermatitis clinical outcome incidence rates",
      "sourceSlides": [
        53,
        54
      ],
      "measure": "Incidence rate",
      "unit": "events per person-year",
      "databaseOrder": [
        "NHIRD",
        "CGRD",
        "NHIS",
        "DeSC",
        "CDARS"
      ],
      "zeroValueNote": "The source slide reports zero values with zero-width confidence intervals for some database-outcome combinations. The underlying zero-event mechanism is not reported.",
      "outcomes": [
        {
          "id": "ad-related-ip-er",
          "label": "AD-related inpatient or emergency-room event",
          "values": {
            "NHIRD": {
              "estimate": 0,
              "lower": 0,
              "upper": 0
            },
            "CGRD": {
              "estimate": 0.06,
              "lower": 0.05,
              "upper": 0.07
            },
            "NHIS": {
              "estimate": 0,
              "lower": 0,
              "upper": 0
            },
            "DeSC": {
              "estimate": 0,
              "lower": 0,
              "upper": 0
            },
            "CDARS": {
              "estimate": 0,
              "lower": 0,
              "upper": 0
            }
          }
        },
        {
          "id": "complications",
          "label": "Complications",
          "values": {
            "NHIRD": {
              "estimate": 0.55,
              "lower": 0.54,
              "upper": 0.56
            },
            "CGRD": {
              "estimate": 0.55,
              "lower": 0.52,
              "upper": 0.58
            },
            "NHIS": {
              "estimate": 0.43,
              "lower": 0.43,
              "upper": 0.44
            },
            "DeSC": {
              "estimate": 0.31,
              "lower": 0.3,
              "upper": 0.32
            },
            "CDARS": {
              "estimate": 0.04,
              "lower": 0.02,
              "upper": 0.07
            }
          }
        },
        {
          "id": "treatment-change",
          "label": "Treatment change",
          "values": {
            "NHIRD": {
              "estimate": 0.3,
              "lower": 0.3,
              "upper": 0.31
            },
            "CGRD": {
              "estimate": 0.03,
              "lower": 0.03,
              "upper": 0.04
            },
            "NHIS": {
              "estimate": 2.46,
              "lower": 2.44,
              "upper": 2.49
            },
            "DeSC": {
              "estimate": 5.54,
              "lower": 5.4,
              "upper": 5.67
            },
            "CDARS": {
              "estimate": 0.1,
              "lower": 0.07,
              "upper": 0.15
            }
          }
        }
      ],
      "notReportedOnSourceSlide": [
        "analysis year",
        "database-specific denominator",
        "reason for reported zero values"
      ]
    },
    "caseDefinitionPrevalence": {
      "title": "Adult 2020 AD and PN prevalence by case definition",
      "sourceSlides": [
        44,
        45,
        46,
        47
      ],
      "measure": "Prevalence",
      "unit": "percent",
      "population": "Adults",
      "year": 2020,
      "databaseOrder": [
        "NHIRD",
        "CGRD",
        "HIRA",
        "DeSC",
        "CDARS"
      ],
      "definitions": [
        {
          "id": "d1",
          "shortLabel": "D1",
          "label": "Any diagnosis"
        },
        {
          "id": "d2",
          "shortLabel": "D2",
          "label": "Two diagnoses within 180 days"
        },
        {
          "id": "d3",
          "shortLabel": "D3",
          "label": "Two diagnoses within 180 days plus systemic AD/PN medication",
          "databaseSpecificNote": "For CDARS, D3 is any diagnosis plus systemic AD medication."
        }
      ],
      "diseases": {
        "AD": {
          "label": "Atopic dermatitis",
          "values": {
            "NHIRD": {
              "d1": 27.65,
              "d2": 10.47,
              "d3": 2.63
            },
            "CGRD": {
              "d1": 4.13,
              "d2": 3,
              "d3": 1.52
            },
            "HIRA": {
              "d1": 20.54,
              "d2": 8.85,
              "d3": 5.25
            },
            "DeSC": {
              "d1": 48.63,
              "d2": 13.21,
              "d3": 2.69
            },
            "CDARS": {
              "d1": 0.092,
              "d2": null,
              "d3": 0.004
            }
          }
        },
        "PN": {
          "label": "Prurigo nodularis",
          "values": {
            "NHIRD": {
              "d1": 1.67,
              "d2": 0.71,
              "d3": 0.35
            },
            "CGRD": {
              "d1": 0.86,
              "d2": 0.625,
              "d3": 0.317
            },
            "HIRA": {
              "d1": 2.69,
              "d2": 1.31,
              "d3": 0.69
            },
            "DeSC": {
              "d1": 0.244,
              "d2": 0.219,
              "d3": 0.019
            },
            "CDARS": {
              "d1": 0.085,
              "d2": null,
              "d3": 0.002
            }
          }
        }
      },
      "nullValueLabel": "Not reported on the source slide",
      "notReportedOnSourceSlides": [
        "denominator",
        "confidence intervals",
        "explanation of the HIRA source marker"
      ]
    }
  }
}